The Expanding Clinical Universe of Polyglutamine Disease
نویسندگان
چکیده
منابع مشابه
Are Polyglutamine Diseases Expanding?
It remains a matter of speculation as to whether the sense CUG-containing RNA and/or the antisense CAG-encoding polyglutamine peptide serves as the pathogenic moiety in Huntington's disease like-2 (HDL2). In this issue of Neuron, Wilburn et al. show that in a HDL2 mouse model, the polyglutamine peptide drives disease progression.
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ژورنال
عنوان ژورنال: The Neuroscientist
سال: 2019
ISSN: 1073-8584,1089-4098
DOI: 10.1177/1073858418822993